學(xué) 術(shù) 報(bào) 告
報(bào)告題目：
Single Cell Gene Therapy and Analysis on Nano-electroporation Chip
報(bào)告時(shí)間：2019年6月27日（星期四）上午11:00
報(bào)告地點(diǎn)：新主樓A849
報(bào)告人 ：常凌乾教授
（北京航空航天大學(xué)生物與醫(yī)院工程學(xué)院）
邀請(qǐng)人 ：徐曄教授
報(bào)告摘要:
One of thecutting-edge multidisciplinary research themes in Biomedical Engineering is todesign and manufacture advanced Bio-Chip for life science, ranging from invitro cell biology toward in vivo medicine. In recent years, nanotechnologiesfacilitate the development of bio-chips and devices which have demonstratedunprecedented capabilities in single cell analysis and manipulation. We haveattempted to design and develop a novel nano-biotechnology,nano-electroporation (NEP), for years. The nanotechnology allows forhigh-throughput, and precisely delivery of gene / drugs into living cells atsingle-cell resolution.
Thein vitro applications of the NEP platform have been demonstrated in the studiesof intracellular cancer biomarker heterogeneity in leukemic cells,cardiomyocytes, T lymphocytes and glioma stem cells. Our latest efforts haveachieved in vivo cell reprogramming for on-body gene therapy and wound healing.The future research of this nano-technique for flexible wearable drug deliveryplatform with the aims to patient-specific gene therapy and regenerativemedicine are discussed.
報(bào)告人簡介:
常凌乾博士，2016年博士畢業(yè)于美國俄亥俄州立大學(xué)生物醫(yī)學(xué)工程系，現(xiàn)為北京航空航天大學(xué)生物與醫(yī)學(xué)工程學(xué)院教授，生物醫(yī)學(xué)工程高精尖中心單細(xì)胞分析納米技術(shù)研究所執(zhí)行副所長。曾擔(dān)任美國北德克薩斯大學(xué)(Universityof North Texas)生物醫(yī)學(xué)工程系助理教授(TenureTrack)。從事生物微機(jī)電系統(tǒng)、基因轉(zhuǎn)染技術(shù)和細(xì)胞微操縱技術(shù)及其在細(xì)胞基因檢測、治療等領(lǐng)域的研究。近五年在國際期刊發(fā)表SCI論文50篇，如NatureNanotechnology, Nano Letters, Small等。獲得了諸多科研獎(jiǎng)勵(lì)和榮譽(yù)，如俄亥俄州立大學(xué)2015年博士最高獎(jiǎng)PresidentialFellowship，北德克薩斯大學(xué)RSGAwards, MINE 2018‘杰出青年科學(xué)家’提名獎(jiǎng)等。兼任SCI期刊BiomedicalEngineering Online副主編（AssociateEditor）和Computersin Biology and Medicine編委(EditorialBoard)，NatureSpringer《ElectroporationProtocol》第三版主編，中國生物醫(yī)學(xué)工程學(xué)會(huì)納米醫(yī)藥分會(huì)青年委員。
